Guan started his career with West Coast LA agency Kresser/Craig after he graduated from the Art Center College of Design in Pasadena, California.

He joined Saatchi & Saatchi Singapore at the height of its success, producing award winning work for Toyota, Navy and P&G under the stewardship of David Droga. The next stint was with Leo Burnett as a CD, during one of the agency's most prolific times which saw its best creative achievements as one of the hottest Asia Pacific agencies by Campaign Brief Asia Rankings, and winning prestigious blue chip accounts like P&G, Singapore Air Force and SingTel. Next up, Guan took on a regional role at Grey Worldwide KL/SG running GSK and won accounts such as Genting and Maybank.

In 2005, Guan joined J. Walter Thompson as Southeast Asia ECD and was later promoted to the additional role of Global ECD for Unilever's Lux. His current responsibilites include global and regional clients such as Abbott Nutrution, Johnson & Johnson, APP, Singapore Navy and Shell. In 2008-2009, he played a critical role in the Asia Pacific Creative Council to achieve Network for the Year in both Adfest and Spikes Asia.

In 2010, Guan became the first Singaporean to serve as a Cannes Outdoor Jury President. He was also the first Asian to serve as a D&AD Jury Foreman and was the second Asian to ever chair a CLIO jury. An engaging speaker and judge, Guan has frequently been invited to awards shows such as the One Show, NY Festival, Spikes and Adfest.

Guan devotes the same passion and energy that goes into his work into mentoring young talents in Asia. He was instrumental in setting up the Singapore Crowbar Awards, AdFest's Young Lotus, and the Award School Asia, which has worked assiduously to foster the nurturing of budding talents in this region.