The One Show

The One Show is the world's most prestigious award show in advertising and design. For over 50 years, the Gold Pencil has been regarded as one of the top prizes in the creative industry. The One Show has a rich legacy of honoring some of the most groundbreaking ideas, created by some of the most remarkable minds in creativity.

2023 One Show - Design

The Outside In Experiment

Agency Area 23, an IPG Health Company / New York + Ritmika Audio Arts / São Paulo + Horizon Therapeutics / Deerfield

Client Horizon Therapeutics

Category

Craft / Animation

Annual ID

OS23_DE062B

About the Work


Gout is an extremely painful disease, but many people don’t know about the dangerous systemic consequences of uncontrolled gout when uric acid crystals build up in vital organs.
With The Outside In Experiment, we sought to visualize both of those realities for the first time using Artificial Intelligence (AI) to create 5 original films.
Each film begins with a person in pain on the outside of their body, goes deeper to reveal vulnerable inner organs and systems, and finally exposes the true culprit—microscopic uric acid crystals being deposited throughout the body. The open-source Deforum Stable Diffusion notebook was used to create the animations. 20 to 50 prompts generated thousands of images, utilizing specific inputs for camera movement and transition, requiring mathematical equations to deliver zooms, waves, pans, and more.
Crafting prompts required discipline, creativity, medical comprehension, and knowledge of historical and contemporary artists to achieve differentiated styles and the correct organs, crystals, patient ethnicities, and ages.
Each film style was tailored to the way a patient described their pain.
A patient who described their pain as hornets inside their hand was brought to life through dark and ominous nature of oil painting, with thick brushstrokes and natural colors; pain that feels like fire was depicted through traditional anatomical illustration, juxtaposing the vivid burning with a clinical drawing style; high-contrast black-and-white imagery depicted the piercing pain of barbed wire and thorns on flesh; the hyper-maximalist style of saturated color and detail illustrated the internal damage during and beyond a gout flare; and 3D futuristic illustration was used to convey the vividness of electric shocks.
While the AI delivered the output, the input was a painstaking and entirely human process, blending the worlds of medicine, pharmaceutical advertising, fine art, and mathematics, to reveal gout’s insidious nature, from the outside in.

2023 Awards

Total Points: 9

Credits

Agency

Area 23, an IPG Health Company / New York

Client

Julie Hernandez
Michael Nagro

Client / Brand

Horizon Therapeutics / Deerfield

Music / Sound Production Company

Ritmika Audio Arts / São Paulo

Copywriter

Ben Birdie

Chief Creative Officer

Tim Hawkey

Executive Creative Director

Jason Graff
Franklin Williams

Group Creative Director

David Adler
Renata Maia

Sound Designer

Henrique Tanji

Account management

Amy Spence
Lacey Henry

Dolby Atmos Mix

Beto Neves

Technologist

Bill Hanff

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